1,2,3,4-四氢-4-异羟基喹啉合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in acetic acid T=27°C; P=760 Torr; 14 h;
参考文献
Martin; Trudell; Arauzo; Allen; LaLoggia; Deng; Schultz; Tan; Bi; Narayanan; Dorn; Koehler; Skolnick; Cook
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4105 - 4117
反应条件
1: With hydrogen; acetic acid; platinum(IV) oxide T=20°C; P=760 Torr; 2: With potassium hydroxide in water 24 h; Heating;
参考文献
Bernabeu, M. Carmen; Diaz, Jose Luis; Jimenez, Oscar; Lavilla, Rodolfo
Synthetic Communications, 2004 , vol. 34, # 1 p. 137 - 149
反应条件
1.1: 60 percent / hydrated CuSO4; copper; sodium hydroxide / H2O / 12 h / 210 °C 2.1: 71 percent / 5 h / Heating 3.1: hydrogen; acetic acid / PtO2 / 20 °C / 760 Torr 3.2: 69 percent / potassium hydroxide / H2O / 24 h / Heating View Scheme
参考文献
Bernabeu, M. Carmen; Diaz, Jose Luis; Jimenez, Oscar; Lavilla, Rodolfo
Synthetic Communications, 2004 , vol. 34, # 1 p. 137 - 149
反应条件
1.1: 71 percent / 5 h / Heating 2.1: hydrogen; acetic acid / PtO2 / 20 °C / 760 Torr 2.2: 69 percent / potassium hydroxide / H2O / 24 h / Heating View Scheme
参考文献
Bernabeu, M. Carmen; Diaz, Jose Luis; Jimenez, Oscar; Lavilla, Rodolfo
Synthetic Communications, 2004 , vol. 34, # 1 p. 137 - 149
