2-(1,3-苯并噻唑-2-基)乙酰胺合成路线 (共 4 条)
反应条件
Lawesson's reagent in toluene 2 h; Heating;
参考文献
Abbotto, Alessandro; Bradamante, Silvia; Facchetti, Antonio; Pagani, Giorgio A.
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5753 - 5772
参考文献
Van Dormael; Nys
Chim. et Ind. Sonderband 21. Congr. Chim. ind. Bruessel 1948 S. 483, 484
反应条件
1: With sulfuric acid
2: With water
Cooling with ice;
参考文献
Telik, Inc.
Patent: US2010/81653 A1, 2010 ;
Location in patent: Page/Page column 15 ;
US 20100081653 A1
反应条件
1: 2 h / 120 °C
2: 8.01 g / 30percent aqueous NH3 / ethanol / 18 h / 20 °C
View Scheme
参考文献
Abbotto, Alessandro; Bradamante, Silvia; Facchetti, Antonio; Pagani, Giorgio A.
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5753 - 5772