1-苄基-5-氧-3-吡咯烷羧酸甲酯合成路线 （共 43 条）
反应条件
1.1: α-chymotrypsine (α-CT) / aq. phosphate buffer / 20 °C / pH 7.4 / low conversion
2.1: BH3-DMS / tetrahydrofuran / -10 - 20 °C
2.2: 64 percent / aq. HCl / tetrahydrofuran; methanol / 1 h / Heating
3.1: 95 percent / H2 / 20 percent Pd(OH)2/C / methanol / 20 °C
View Scheme
参考文献
Felluga, Fulvia; Pitacco, Giuliana; Prodan, Massimo; Pricl, Sabrina; Visintin, Marco; Valentin, Ennio
Tetrahedron Asymmetry, 2001 , vol. 12, # 23 p. 3241 - 3249
反应条件
α-chymotrypsine (α-CT) in phosphate buffer
T=20°C; pH=7.4; low conversion;
参考文献
Felluga, Fulvia; Pitacco, Giuliana; Prodan, Massimo; Pricl, Sabrina; Visintin, Marco; Valentin, Ennio
Tetrahedron Asymmetry, 2001 , vol. 12, # 23 p. 3241 - 3249
反应条件
1: 28 percent / α-chymotrypsine (α-CT) / aq. phosphate buffer / 20 °C / pH 7.4 / low conversion
View Scheme
参考文献
Felluga, Fulvia; Pitacco, Giuliana; Prodan, Massimo; Pricl, Sabrina; Visintin, Marco; Valentin, Ennio
Tetrahedron Asymmetry, 2001 , vol. 12, # 23 p. 3241 - 3249
