(3-硝基苯基)肼氯化物合成路线 （共 13 条）
参考文献
Macor, John E.
Patent: US6255306 B1, 2001 ;
US 6255306 B1
反应条件
1.1: ethanol / 4 h / 20 °C 2.1: PPA / toluene / Reflux 2.2: Reflux 2.3: pH 1 - 2 View Scheme
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
US 20120309758 A1
反应条件
acetic acid in water T=0°C; 20 h;
参考文献
Aebi, Johannes; Binggeli, Alfred; Green, Luke; Hartmann, Guido; Maerki, Hans P.; Mattei, Patrizio; Ricklin, Fabienne; Roche, Olivier
Patent: US2009/29963 A1, 2009 ;
Location in patent: Page/Page column 29 ;
US 20090029963 A1
参考文献
Icos Corporation
Patent: US6569885 B1, 2003 ;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
US 20120309758 A1
反应条件
1: 10 percent NaOH / ethanol; acetic acid / 1 h / 20 °C 2: 85 percent H3PO4 / toluene / 9 h / 100 °C View Scheme
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
US 20120309758 A1
反应条件
in ethanol T=20°C; 4 h;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
Location in patent: Page/Page column 67 ;
US 20120309758 A1
反应条件
Bi(NO3)3; PPA in methanol 2.5 h; Reflux;
参考文献
Sudhakara; Jayadevappa; Mahadevan; Hulikal, Vijaykumar
Synthetic Communications, 2009 , vol. 39, # 14 p. 2506 - 2515
反应条件
1: ethanol / 4 h / 20 °C 2: PPA / toluene / Reflux View Scheme
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
US 20120309758 A1
