triethylamine in N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
Tsuboi, Katsunori; Bachovchin, Daniel A.; Speers, Anna E.; Spicer, Timothy P.; Fernandez-Vega, Virneliz; Hodder, Peter; Rosen, Hugh; Cravatt, Benjamin F.
Journal of the American Chemical Society, 2011 , vol. 133, # 41 p. 16605 - 16616
Mikhura, I. V.; Formanovskii, A. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 2 p. 205 - 212
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 2 p. 247 - 255
Gavande, Navnath; Kim, Hye-Lim; Doddareddy, Munikumar R.; Johnston, Graham A. R.; Chebib, Mary; Hanrahan, Jane R.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 402 - 407
1: 96 percent / MgO, H2O / dioxane / 26 h / 50 °C 2: 55 percent / DCC / 1,2-dimethoxy-ethane / 20 h / 0 °C View Scheme
参考文献
Mikhura, I. V.; Formanovskii, A. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 2 p. 205 - 212
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 2 p. 247 - 255
1: 54 percent / pyridine / 18 h / 20 °C
2: aq. TFA / 1 h / 20 °C
View Scheme
参考文献
Gussin, Helene A.; Tomlinson, Ian D.; Little, Deborah M.; Warnement, Michael R.; Qian, Haohua; Rosenthal, Sandra J.; Pepperberg, David R.
Journal of the American Chemical Society, 2006 , vol. 128, # 49 p. 15701 - 15713
1: 94 percent / 1,2-dimethoxy-ethane / 3 h
2: 100 percent / H2, AcOH / 10percent Pd/C / methanol / 1 h / 760 Torr
3: 90 percent / DCC / ethyl acetate / 3 h / 0 - 20 °C
4: 0.25 h / 50 °C
5: Et3N / dimethylformamide / 4 h / 60 °C
View Scheme
参考文献
Mikhura, I. V.; Formanovskii, A. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 2 p. 205 - 212
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 2 p. 247 - 255
