[双(甲硫基)亚甲基]丙烷二腈合成路线 （共 52 条）
反应条件
potassium carbonate; tetrabutylammomium bromide in benzene T=60°C; 3 h;
参考文献
El-Shafei, Ahmed Kamal; Soliman, Ahmed Mohamed; Sultan, Adel Abdel-Rahim; El-Saghier, Ahmed Mohamed Mohamed
Gazzetta Chimica Italiana, 1995 , vol. 125, # 3 p. 115 - 118
反应条件
1: carbon disulfide; malononitrile With sodium ethanolate in ethanol T=20°C; 1 h; 2: dimethyl sulfate in ethanol
参考文献
Yu, Shen-Yi; Cai, Ya-Xian
Synthetic Communications, 2003 , vol. 33, # 22 p. 3989 - 3995
反应条件
carbon disulfide; sodium methylate in methanol
参考文献
Sterling Winthrop Inc.
Patent: US5294612 A1, 1994 ;
反应条件
alcoholic sodium methoxide
参考文献
Smith Kline and French Laboratories Limited
Patent: US4046907 A1, 1977 ;
US 4046907 A
参考文献
FMC Corporation
Patent: US4075001 A1, 1978 ;
反应条件
in water T=25 - 30°C; 72 h;
参考文献
D'Amico, J. J.; Ruminski, P. G.; Suba, L. A.; Freeman, J. J.; Dahl, W. E.
Phosphorus and Sulfur and the Related Elements, 1984 , vol. 21, p. 307 - 314
反应条件
tetrabutylammomium bromide in N,N-dimethyl-formamide T=60°C; 64 h; Inert atmosphere;
参考文献
Lethu, Sebastien; Dubois, Joelle
European Journal of Organic Chemistry, 2011 , # 20-21 p. 3920 - 3931
反应条件
1: carbon disulfide; 2,4-dioxo-pentanedinitrile With potassium carbonate in N,N-dimethyl-formamide T=0 - 20°C; 0.5 h; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; 8.25 h;
参考文献
Liu, Yingjie; Liu, Jingxin; Wang, Mang; Liu, Jun; Liu, Qun
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 14-15 p. 2678 - 2682
参考文献
Yokoyama, Masataka; Kumata, Katsushi; Yamada, Naoyuki; Noro, Hidehiko; Sudo, Yuka
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2309 - 2314
参考文献
Takeshima,T. et al.
Journal of Organic Chemistry, 1970 , vol. 35, p. 2438 - 2440
