(S)-(+)-2-氨基丁烷合成路线 （共 39 条）
反应条件
[3H]-L-Alanine; Bacillus subtilis L-alanine dehydrogenase; NAD-specific formate dehydrogenase; ω-transaminase ATA-113; pyridoxal 5'-phosphate; ammonium formate; β-nicotinamide adenine dinucleotide in dimethyl sulfoxide T=30°C; pH=7; 24 h; aq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Mutti, Francesco G.; Fuchs, Christine S.; Pressnitz, Desiree; Turrini, Nikolaus G.; Sattler, Johann H.; Lerchner, Alexandra; Skerra, Arne; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2012 , # 5 p. 1003 - 1007
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Santaniello, Enzo; Casati, Rosangela; Milani, Fulvia
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 919 - 922
反应条件
Aspergillus niger AC-54 lipase in hexane T=50°C; P=2585.81 Torr; 0.0166667 h; Microwave irradiationEnzymatic reaction;
参考文献
Pilissao, Cristiane; De Oliveira Carvalho, Patricia; Da Graca Nascimento, Maria
Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 9 p. 1688 - 1697
反应条件
Aspergillus niger AC-54 lipase in hexane T=50°C; P=2585.81 Torr; 0.0166667 h; Microwave irradiationEnzymatic reaction;
参考文献
Pilissao, Cristiane; De Oliveira Carvalho, Patricia; Da Graca Nascimento, Maria
Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 9 p. 1688 - 1697
反应条件
Candida antarctica lipase B in n-heptane T=80°C; 6 h;
参考文献
Nechab, Malek; Azzi, Nadia; Vanthuyne, Nicolas; Bertrand, Michele; Gastaldi, Stephane; Gil, Gerard
Journal of Organic Chemistry, 2007 , vol. 72, # 18 p. 6918 - 6923
反应条件
methanol; platinum(IV) oxide P=2206.5 Torr; Hydrogenation;
参考文献
Levene; Rothen
Journal of Biological Chemistry, 1936 , vol. 115, p. 426
反应条件
Escherichia coli overexpressing ω-transaminase from round 11 variant from Arthrobacter sp.; pyridoxal 5'-phosphate; isopropylamine in dimethyl sulfoxide T=45°C; pH=11; aq. bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Mutti, Francesco G.; Fuchs, Christine S.; Pressnitz, Desiree; Sattler, Johann H.; Kroutil, Wolfgang
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 17 p. 3227 - 3233
反应条件
1: With transaminase ATA-117; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; 2: With [3H]-L-Alanine; transaminase ATA-113 T=30°C; 24 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
transaminase ATA-117; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
supported Candida antartica lipase B in tert-butyl methyl ether T=38 - 40°C; 3 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Poulhes, Florent; Vanthuyne, Nicolas; Bertrand, Michele P.; Gastaldi, Stephane; Gil, Gerard
Journal of Organic Chemistry, 2011 , vol. 76, # 17 p. 7281 - 7286
