4-溴-3,5-二甲基-1-苯基-1H-吡唑合成路线 （共 7 条）
反应条件
N-bromosuccinmide in ethyl acetate
T=25 - 30°C; 0.25 h; ultrasound irradiation;
参考文献
Bernhammer, Jan Christopher; Huynh, Han Vinh
Dalton Transactions, 2012 , vol. 41, # 28 p. 8600 - 8608
反应条件
bromine in acetic acid
0.5 h; Ambient temperature;
参考文献
Khan; Mustafa
Pharmazie, 1986 , vol. 41, # 11 p. 813 - 814
反应条件
1: ethanol / 16 h / Reflux
2: N-bromosuccinmide / ethyl acetate / 0.5 h / 20 °C / Sonication
View Scheme
参考文献
Bernhammer, Jan Christopher; Huynh, Han Vinh
Dalton Transactions, 2012 , vol. 41, # 28 p. 8600 - 8608
反应条件
1: ethanol / 16 h / Reflux
2: N-bromosuccinmide / ethyl acetate / 0.5 h / 20 °C / Sonication
View Scheme
参考文献
Bernhammer, Jan Christopher; Huynh, Han Vinh
Dalton Transactions, 2012 , vol. 41, # 28 p. 8600 - 8608
反应条件
hydrogenchloride in ethanol
Heating;
参考文献
Svistunova; Shapkin; Nikolaeva; Apanasenko
Russian Journal of General Chemistry, 2011 , vol. 81, # 4 p. 756 - 761
反应条件
in tetrahydrofuran
T=-78 - 0°C;
参考文献
Calle; Cuadrado; Gonzalez-Nogal; Valero
Synthesis, 2001 , # 13 p. 1949 - 1958
反应条件
1: 4-bromo-3,5-dimethyl-1-phenyl-1H-pyrazole With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran
T=-78°C; 5 h;
2: dimethyl(phenyl)silyl chloride in tetrahydrofuran
T=-78 - 0°C;
参考文献
Calle; Cuadrado; Gonzalez-Nogal; Valero
Synthesis, 2001 , # 13 p. 1949 - 1958
