2-(4-氯苯基)苯并恶唑-5-丙腈合成路线 （共 4 条）
反应条件
hydrogenchloride 2.5 h; Heating;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
sodium azide; ammonium chloride in N,N-dimethyl-formamide
T=125°C; 24 h;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: aq. HCl / 2.5 h / Heating
2: TsOH / benzene / 12 h / Heating
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: aq. HCl / 2.5 h / Heating
2: TsOH / benzene / 12 h / Heating
3: NH3 / glycerol / 17 h / 150 °C
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
