2-(3-氨基-4-羟基苯基)丙腈合成路线 (共 30 条)
反应条件
1: Py 2: aq. HCl / 2.5 h / Heating View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
参考文献
Browner; Cockerill; Maidment; Rackham; Snook
Journal of Pharmaceutical Sciences, 1976 , vol. 65, # 9 p. 1305 - 1309
反应条件
1: Py
2: NaN3, NH4Cl / dimethylformamide / 24 h / 125 °C
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: aq. HCl / Heating
2: Py
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
(i) Py, (ii) aq. HCl; Multistep reaction;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
(i) Py, (ii) aq. HCl; Multistep reaction;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: aq. HCl / Heating
2: Py
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: aq. HCl / Heating
2: HCl / Heating
3: Py
4: aq. NaOH / ethanol / 4.5 h / Ambient temperature
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
参考文献
FGN, INC.; THE UNIVERSITY OF ARIZONA
Patent: EP485173 A2, 1992 ;
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58