2-(4-羟基-3-硝基苯基)丁腈合成路线 （共 31 条）
反应条件
1: SnCl2, aq. HCl / ethanol 2: Py 3: aq. HCl / 2.5 h / Heating View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
nitric acid in acetic acid
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
参考文献
Lilly Industries, Ltd.
Patent: US3962441 A1, 1976 ;
反应条件
1: (i) NaNO2, aq. HCl, (ii) aq. H2SO4
2: HNO3 / acetic acid
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: Py
3: NaN3, NH4Cl / dimethylformamide / 24 h / 125 °C
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: aq. HCl / Heating
3: Py
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: (i) Py, (ii) aq. HCl
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: (i) Py, (ii) aq. HCl
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: aq. HCl / Heating
3: Py
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
反应条件
1: SnCl2, aq. HCl / ethanol
2: aq. HCl / Heating
3: HCl / Heating
4: Py
5: aq. NaOH / ethanol / 4.5 h / Ambient temperature
View Scheme
参考文献
Dunwell,D.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, # 1 p. 53 - 58
