叔丁氧羰基-D-天冬氨酸 4-苄酯合成路线 （共 5 条）
反应条件
sodium hydroxide; triethylamine in water; acetone T=20°C; 0.0333333 h;
参考文献
Sato, Shinichi; Tetsuhashi, Masashi; Sekine, Keiko; Miyachi, Hiroyuki; Naito, Mikihiko; Hashimoto, Yuichi; Aoyama, Hiroshi
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 8 p. 4685 - 4698
参考文献
Munekata; Shiba; Kaneko
Bulletin of the Chemical Society of Japan, 1973 , vol. 46, # 12 p. 3835 - 3839
反应条件
1: boron trifluoride diethyl etherate / dichloromethane; cyclohexane 2: palladium 10 on activated carbon; hydrogen / ethanol / 2585.81 Torr View Scheme
参考文献
Qu, Wenchao; Zha, Zhihao; Ploessl, Karl; Lieberman, Brian P.; Zhu, Lin; Wise, David R.; Thompson, Craig B.; Kung, Hank F.
Journal of the American Chemical Society, 2011 , vol. 133, # 4 p. 1122 - 1133
反应条件
trifluoroacetic acid in dichloromethane 2 h; Ambient temperature;
参考文献
Liotta; Gibbs; Taylor; Benkovic
Journal of the American Chemical Society, 1995 , vol. 117, # 17 p. 4729 - 4741
反应条件
1: triethylamine / tetrahydrofuran / 0 °C
2: sodium tetrahydroborate / water / 1 h / 20 °C
3: palladium 10 on activated carbon; hydrogen / 20 °C
View Scheme
参考文献
Yoshikawa, Kenji; Yoshino, Toshiharu; Yokomizo, Yoshihiro; Uoto, Kouichi; Naito, Hiroyuki; Kawakami, Katsuhiro; Mochizuki, Akiyoshi; Nagata, Tsutomu; Suzuki, Makoto; Kanno, Hideyuki; Takemura, Makoto; Ohta, Toshiharu
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 2133 - 2140
