hydrogen; palladium on activated charcoal in tetrahydrofuran P=2585.7 Torr; 1.5 h; Ambient temperature;

1: m-chloroperbenzoic acid / CH2Cl2 / 2 h / 35 °C 2: 1.) potassium tert-butoxide, 2.) HCl / 1.) THF, 15 deg C, 2 h; 2.) THF, 15 deg C, 20 min 3: 100 percent / H2 / Pd/C / tetrahydrofuran / 1.5 h / 2585.7 Torr / Ambient temperature View Scheme

1: LiBr / dimethylformamide / 5 h / 80 - 100 °C 2: m-chloroperbenzoic acid / CH2Cl2 / 2 h / 35 °C 3: 1.) potassium tert-butoxide, 2.) HCl / 1.) THF, 15 deg C, 2 h; 2.) THF, 15 deg C, 20 min 4: 100 percent / H2 / Pd/C / tetrahydrofuran / 1.5 h / 2585.7 Torr / Ambient temperature View Scheme

1: 1.) potassium tert-butoxide, 2.) HCl / 1.) THF, 15 deg C, 2 h; 2.) THF, 15 deg C, 20 min 2: 100 percent / H2 / Pd/C / tetrahydrofuran / 1.5 h / 2585.7 Torr / Ambient temperature View Scheme

1H-imidazole; Mn(TDCPP)Cl; dihydrogen peroxide in dichloromethane; acetonitrile T=20°C; 4 h;

Vitamin C; Agrocybe aegerita peroxygenase; dihydrogen peroxide T=20°C; pH=7; 0.05 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;

cytochrome P450 2C9; NADPH T=37°C; 20 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;