(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺合成路线

511256-31-8→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

Kanai, Masatomi; Yasumoto, Manabu; Kuriyama, Yokusu; Inomiya, Kenjin; Katsuhara, Yutaka; Higashiyama, Kimio; Ishii, Akihiro
Organic Letters, 2003 , vol. 5, # 7 p. 1007 - 1010

290297-43-7N-甲基-1-[3,5-(双三氟甲基)苯基]乙胺→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

PFIZER PRODUCTS INC.
Patent: WO2004/110996 A1, 2004 ;
Location in patent: Page/Page column 25 ;
WO 2004/110996 A1

1453070-37-5→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

LEO PHARMA A/S; SØRENSEN, Morten, Dahl; DI FABIO, Romani; POZZAN, Alfonso; CATALANI, Maria, Pia; BLADH, Haakon; FELDING, Jakob
Patent: WO2013/124286 A1, 2013 ;
Location in patent: Page/Page column 126; 127 ;

1333317-69-3→334477-60-0(R)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺+511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

THE UNIVERSITY OF SHEFFIELD; JONES, Simon; LI, Xianfu
Patent: WO2013/79942 A1, 2013 ;
Location in patent: Page/Page column 29; 30 ;

737786-85-5+74-89-5甲胺→334477-60-0(R)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺+511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

AVECIA PHARMACEUTICALS LIMITED
Patent: WO2006/67395 A1, 2006 ;
Location in patent: Page/Page column 22-23 ;

30071-93-33,5-双三氟甲基苯乙酮→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

Kanai, Masatomi; Yasumoto, Manabu; Kuriyama, Yokusu; Inomiya, Kenjin; Katsuhara, Yutaka; Higashiyama, Kimio; Ishii, Akihiro
Organic Letters, 2003 , vol. 5, # 7 p. 1007 - 1010

672906-98-8→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

Kanai, Masatomi; Yasumoto, Manabu; Kuriyama, Yokusu; Inomiya, Kenjin; Katsuhara, Yutaka; Higashiyama, Kimio; Ishii, Akihiro
Organic Letters, 2003 , vol. 5, # 7 p. 1007 - 1010

384824-41-3→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

Kanai, Masatomi; Yasumoto, Manabu; Kuriyama, Yokusu; Inomiya, Kenjin; Katsuhara, Yutaka; Higashiyama, Kimio; Ishii, Akihiro
Organic Letters, 2003 , vol. 5, # 7 p. 1007 - 1010

401-95-63,5-双三氟甲基苯甲醛→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

LEO PHARMA A/S; SØRENSEN, Morten, Dahl; DI FABIO, Romani; POZZAN, Alfonso; CATALANI, Maria, Pia; BLADH, Haakon; FELDING, Jakob
Patent: WO2013/124286 A1, 2013 ;

1453070-36-4→511256-36-3(S)-N-甲基-1-[3,5-二(三氟甲基)苯基]乙胺

参考文献

LEO PHARMA A/S; SØRENSEN, Morten, Dahl; DI FABIO, Romani; POZZAN, Alfonso; CATALANI, Maria, Pia; BLADH, Haakon; FELDING, Jakob
Patent: WO2013/124286 A1, 2013 ;