2alpha-(3,4-二甲氧基苯基)-5,7-二甲氧基-3,4-二氢-2H-1-苯并吡喃-3beta-醇合成路线 （共 9 条）
反应条件
dipotassium peroxodisulfate; copper(II) sulfate in water; acetonitrile 0.916667 h; Heating;
参考文献
Tetrahedron, , vol. 46, # 19 p. 6885 - 6894
反应条件
1,3,5-trishydroxybenzene in acetone 2.5 h; Irradiation;
参考文献
Journal of Photochemistry and Photobiology A: Chemistry, , vol. 227, # 1 p. 18 - 24
参考文献
v. Kostanecki; Lampe
Chemische Berichte, 1906 , vol. 39, p. 4017
反应条件
1.1: NaH / dimethylformamide / 0.25 h / 10 °C 1.2: 88 percent / dimethylformamide / 0.33 h / 20 °C 2.1: 80 percent / Bu3SnH; AIBN / toluene / 8.25 h / Heating 3.1: 87 percent / NBS / CH2Cl2 / 1.83 h / -70 - -16 °C 4.1: t-BuLi / tetrahydrofuran; pentane / 0.07 h / -78 °C 4.2: tetrahydrofuran; pentane / 1.67 h / -78 - -10 °C 4.3: H2 / Pd(OH)2/C / methanol; ethyl acetate / 6 h / 20 °C / 750.08 Torr 5.1: NaIO4; RuCl3*xH2O / CCl4; acetonitrile; H2O / 2 h / 20 °C 5.2: tetrahydrofuran; methanol / 65 h / 20 °C View Scheme
参考文献
Kozikowski, Alan P.; Tueckmantel, Werner; George, Clifford
Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5371 - 5381
参考文献
Journal of the Chemical Society, , vol. 87, p. 399
Chemische Berichte, , vol. 39, p. 4017
参考文献
Chemische Berichte, , vol. 39, p. 4017
反应条件
1,4-dioxane; bromine Erwaermen des jeweiligen Reaktionsprodukts mit wss. Jodwasserstoffsaeure, Phenol und Phosphor unter Kohlendioxid; Behandeln des erhaltenen Jodids mit Silberchlorid in wss.-aethanol. Salzsaeure;
参考文献
Appel; Robinson
Journal of the Chemical Society, 1935 , p. 426,428
反应条件
hydrogenchloride in 1,4-dioxane
参考文献
Weinges,K.; Nagel,D.
Chemische Berichte, 1968 , vol. 101, p. 3018 - 3021
反应条件
1.1: NaH / dimethylformamide / 0.25 h / 10 °C
1.2: 88 percent / dimethylformamide / 0.33 h / 20 °C
2.1: 80 percent / Bu3SnH; AIBN / toluene / 8.25 h / Heating
3.1: 87 percent / NBS / CH2Cl2 / 1.83 h / -70 - -16 °C
4.1: t-BuLi / tetrahydrofuran; pentane / 0.07 h / -78 °C
4.2: tetrahydrofuran; pentane / 1.67 h / -78 - -10 °C
4.3: H2 / Pd(OH)2/C / methanol; ethyl acetate / 6 h / 20 °C / 750.08 Torr
5.1: NaIO4; RuCl3*xH2O / CCl4; acetonitrile; H2O / 2 h / 20 °C
5.2: tetrahydrofuran; methanol / 65 h / 20 °C
View Scheme
参考文献
Kozikowski, Alan P.; Tueckmantel, Werner; George, Clifford
Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5371 - 5381
