N-(2-氰基乙基)-L-缬氨酸合成路线 （共 2 条）
反应条件
1: N-(2-cyanoethyl)-L-valine With sodium hydroxide in water pH=9.5 - 10.5; 2: methyl chloroformate With sodium hydroxide in water T=20 - 25°C; pH=9.0 - 10.5;
参考文献
CLARIANT LIFE SCIENCE MOLECULES (ITALIA) S.P.A.
Patent: WO2003/101971 A1, 2003 ;
Location in patent: Page 7 ;
反应条件
1: 2-aminoisovaleric acid With potassium hydroxide in water
T=20°C;
2: acrylonitrile in water
T=0 - 5°C; 4.5 - 5.5 h;
参考文献
CLARIANT LIFE SCIENCE MOLECULES (ITALIA) S.P.A.
Patent: WO2003/101971 A1, 2003 ;
Location in patent: Page 6 ;
