(-)-Boc-L-硫代脯氨酸合成路线 （共 5 条）
反应条件
triethylamine in water; acetonitrile T=20°C; 18 h;
参考文献
GLENMARK PHARMACEUTICALS LTD.
Patent: WO2005/58849 A1, 2005 ;
Location in patent: Page/Page column 40 ;
WO 2005/058849 A1
反应条件
sodium chloride in ethanol
参考文献
Ono Pharmaceutical Co., Ltd
Patent: US6605608 B1, 2003 ;
US 6605608 B1
反应条件
hydrogenchloride; sodium hydrogencarbonate in 1,4-dioxane; water
参考文献
American Cyanamid Company
Patent: US4374249 A1, 1983 ;
US 4374249 A
反应条件
1: formaldehyd; (R)-cysteine With sodium hydroxide 2: di-tert-butyl dicarbonate With sodium hydroxide in 1,4-dioxane; water
参考文献
Rambo, Raoni S.; Schneider, Paulo H.
Tetrahedron Asymmetry, 2010 , vol. 21, # 18 p. 2254 - 2257
反应条件
1: With formic acid T=0 - 20°C; 10 h; 2: With sodium hydrogencarbonate
参考文献
Vishnumaya, Monika Raj; Singh, Vinod K.
Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4289 - 4297
