4-(3,4-二甲基苯基)-4-氧丁酸合成路线 （共 9 条）
反应条件
[bmim]Cl*AlCl3 T=30°C; Friedel-Crafts reaction; 3 h;
参考文献
Mohile, Swapnil S.; Potdar, Mahesh K.; Salunkhe, Manikrao M.
Journal of Chemical Research - Part S, 2003 , # 10 p. 650 - 651
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5716944 A1, 1998 ;
反应条件
(i) N2H4, KOH, HOCH2CH2OH, (ii) polyphosphoric acid; Multistep reaction;
参考文献
Barnett; Sanders
Journal of the Chemical Society, 1933 , p. 434,436
反应条件
sodium hydroxide; sodium hydrogencarbonate; sodium carbonate; potassium hexacyanoferrate(III); osmium(VIII) oxide in water T=36.85°C; pH=10.33; Kinetics; Further Variations:pH-values;
参考文献
Gnana Rani, D. Freeda; Pushparaj, F. J. Maria; Alphonse; Rangappa
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 10 p. 2153 - 2159
反应条件
sodium hydroxide; sodium hydrogencarbonate; sodium carbonate; potassium hexacyanoferrate(III); osmium(VIII) oxide in water T=36.85°C; pH=10.33; Kinetics; Further Variations:pH-values;
参考文献
Gnana Rani, D. Freeda; Pushparaj, F. J. Maria; Alphonse; Rangappa
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 10 p. 2153 - 2159
反应条件
sodium hydroxide; sodium hypochlorite
参考文献
Reinheimer; List
Ohio Journal of Science, 1957 , vol. 57, p. 26
反应条件
acetyl chloride
0.25 h; Heating;
参考文献
Tsolomitis, A.; Sandris, C.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1545 - 1548
反应条件
potassium hydroxide; hydrazine hydrate in various solvent(s)
1) 2 h, reflux, 2) 180-190 deg C, ca. 4 h;
参考文献
Boberg, Friedrich; Jachiewicz, Adam; Garming, Alfons
Phosphorus, Sulfur and Silicon and the Related Elements, 1992 , vol. 72, # 1-4 p. 1 - 12
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5716944 A1, 1998 ;
