3,4-二氢化-6-甲基-1(2H)-萘酮合成路线 （共 30 条）
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=105°C; Inert atmosphere;
参考文献
BARBOSA, Joseph; CARSON, Kenneth Gordon; GARDYAN, Michael Walter; HEALY, Jason Patrick; HAN, Qiang; MABON, Ross; PABBA, Praveen; TARVER, JR., James; TERRANOVA, Kristen M.; TUNOORI, Ashok; XU, Xiaolian
Patent: US2012/302562 A1, 2012 ;
Location in patent: Page/Page column 18 ;
US 20120302562 A1
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane
T=20°C; 0.166667 h;
参考文献
Shim, Seung-Bo; Ko, Yoon-Joo; Yoo, Byeong-Wook; Lim, Chang-Keun; Shin, Jung-Hyu
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8154 - 8156
反应条件
trifluorormethanesulfonic acid
T=5 - 20°C; Cyclization; 2 h;
参考文献
Orita, Akihiro; Yaruva, Jayamma; Otera, Junzo
Angewandte Chemie - International Edition, 1999 , vol. 38, # 15 p. 2267 - 2270
反应条件
bis-triphenylphosphine-palladium(II) chloride; 2,6-di-tert-butyl-4-methyl-phenol; lithium chloride in N,N-dimethyl-formamide
T=90°C; 18 h;
参考文献
Almansa; Carceller; Bartroli; Forn
Synthetic Communications, 1993 , vol. 23, # 21 p. 2965 - 2971
反应条件
silver trifluoromethanesulfonate in dichloromethane
20 h; Ambient temperature;
参考文献
Manas, Abdul Rahman Bin; Smith, Robin A. J.
Tetrahedron, 1987 , vol. 43, # 8 p. 1847 - 1856
反应条件
1: 97 percent / OXONE; H2O / tetrahydrofuran / 12 h / 0 - 20 °C
2: 97 percent / TfOH / 2 h / 5 - 20 °C
View Scheme
参考文献
Orita, Akihiro; Yaruva, Jayamma; Otera, Junzo
Angewandte Chemie - International Edition, 1999 , vol. 38, # 15 p. 2267 - 2270
反应条件
chromium(VI) oxide; acetic acid
参考文献
Jackman,L.M.; Haddon,V.R.
Journal of the American Chemical Society, 1974 , vol. 96, # 16 p. 5130 - 5138
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid; lithium iodide in tetrachloromethane
16 h; Heating;
参考文献
Das, Jagabandhu; Valenta, Zdenek; Liu, Hsing-Jang; Ngooi, Teng Ko
Canadian Journal of Chemistry, 1984 , vol. 62, p. 481 - 483
反应条件
1: diethyl ether / Behandeln des Reaktionsprodukts mit wss. Kalilauge
2: amalgamated zinc; aqueous hydrochloric acid; toluene
3: SOCl2 / Behandeln des Reaktionsprodukts in Schwefelkohlenstoff mit AlCl3
View Scheme
参考文献
Fieser; Dunn
Journal of the American Chemical Society, 1936 , vol. 58, p. 572,575
反应条件
1: (i) HCO2H, sodium formate, (ii) LiAlH4
2: CrO3, AcOH
View Scheme
参考文献
Jackman,L.M.; Haddon,V.R.
Journal of the American Chemical Society, 1974 , vol. 96, # 16 p. 5130 - 5138
