反应条件
1: 1.) acetic anhydride, 2.) 2N HCl / 1.) glacial acetic acid, reflux, 5.5 h, 2.) reflux, 3 h
2: 77 percent / HCl (gas) / 5 h / Heating
3: 87 percent / Et3N / dioxane; H2O / 15 h / 50 °C
4: 89 percent / pyridine / 1.) 0 deg C, 1 h, 2.) room temperature, 48 h
5: 1.) Et4NOAc*4H2O, 2.) 1 N NaOH / 1.) benzene, reflux, 1.5 h, 2.) MeOH, 0 deg C
6: 45 percent / LiBH4 / tetrahydrofuran
7: 69 percent / pyridine
8: 34 percent / 1.) Na/NH3 (liq.) / tetrahydrofuran
View Scheme
参考文献
Baker, Gregory L.; Fritschel, Scott J.; Stille, John R.; Stille, John K.
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2954 - 2960
