3-氯-6-(1H-吡咯-1-基)哒嗪合成路线 (共 2 条)
反应条件
1: pyrrole With sodium hydride in N,N-dimethyl-formamide; mineral oil T=20°C; 0.0833333 h; Schlenk technique; 2: 3,6-dichloro-pyridazine in N,N-dimethyl-formamide; mineral oil T=20°C; Schlenk technique;
参考文献
Sengmany, Stephane; Vitu-Thiebaud, Arnaud; Le Gall, Erwan; Condon, Sylvie; Leonel, Eric; Thobie-Gautier, Christine; Pipelier, Muriel; Lebreton, Jacques; Dubreuil, Didier
Journal of Organic Chemistry, 2013 , vol. 78, # 2 p. 370 - 379
反应条件
acetic acid T=120°C; 1 h;
参考文献
Steiner; Gries; Lenke
Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 59 - 63