1-(3,4-二甲氧基苯基)乙胺合成路线 （共 8 条）
参考文献
INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
Patent: EP2511283 A1, 2012 ;
Location in patent: Page/Page column 66 ;
反应条件
1: in tetrahydrofuran; diethyl ether T=100°C; 0.166667 h; Microwave irradiation; 2: With sodium tetrahydroborate in tetrahydrofuran; methanol; diethyl ether 0.0833333 h;
参考文献
Gregg, Brian T.; Golden, Kathryn C.; Quinn, John F.; Wang, Hong-Jun; Zhang, Wei; Wang, Ruifang; Wekesa, Francis; Tymoshenko, Dmytro O.
Tetrahedron Letters, 2009 , vol. 50, # 27 p. 3978 - 3981
反应条件
4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; ammonium formate in methanol T=80°C; 12 h; Inert atmosphere; chemoselective reaction;
参考文献
Talwar, Dinesh; Salguero, Noemi Poyatos; Robertson, Craig M.; Xiao, Jianliang
Chemistry - A European Journal, 2014 , vol. 20, # 1 p. 245 - 252
反应条件
hydrogenchloride 1 h; Heating;
参考文献
Ho, Bin; Michael Crider; Stables, James P
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 265 - 286
反应条件
sodium hydroxide Yield given;
参考文献
Davis, Franklin A.; Giangiordano, Mark A.; Starner, William E.
Tetrahedron Letters, 1986 , vol. 27, # 34 p. 3957 - 3960
反应条件
2: aq. NaOH / ethanol View Scheme
参考文献
Kametani,T.; Fukumoto,K.
Journal of the Chemical Society, 1963 , p. 4289 - 4296
反应条件
(R)-(-)-α-hydroxybenzeneacetic acid Resolution of racemate;
参考文献
NEUROGEN CORPORATION
Patent: WO2006/15279 A1, 2006 ;
Location in patent: Page/Page column 44 ;
WO 2006/015279 A1
反应条件
pyridine; sodium borohydride; benzaldehyde in methanol
参考文献
Chinoin Gyogyszer es Vegyeszeti Termekek Gyar RT
Patent: US4988730 A1, 1991 ;
