反应条件
1: in tetrahydrofuran; diethyl ether
T=-78°C; 0.333333 h;
2: With n-butyllithium in pentane
T=-78°C; 0.5 h;
3: With 1,2,2-trichloro-1,1,2-trichloro-ethane in tetrahydrofuran
T=-78 - 20°C; 3 h;
参考文献
Zhang, Han-Zhong; Kasibhatla, Shailaja; Kuemmerle, Jared; Kemnitzer, William; Ollis-Mason, Kristin; Qiu, Ling; Crogan-Grundy, Candace; Tseng, Ben; Drewe, John; Cai, Sui Xiong
Journal of Medicinal Chemistry, 2005 , vol. 48, # 16 p. 5215 - 5223
