4-溴-2-氯-N,N-二甲基苯胺合成路线 (共 3 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=100°C;
参考文献
Li, James J.; Norton, Monica B.; Reinhard, Emily J.; Anderson, Gary D.; Gregory, Susan A.; Isakson, Peter C.; Koboldt, Carol M.; Masferrer, Jaime L.; Perkins, William E.; Seibert, Karen; Zhang, Yan; Zweifel, Ben S.; Reitz, David B.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 9 p. 1846 - 1856
反应条件
in N,N-dimethyl-formamide
参考文献
G.D. Searle and Co.
Patent: US5739166 A1, 1998 ;
反应条件
trichloroisocyanuric acid
20 h; Ambient temperature;
参考文献
Rosevear, Judi; Wilshire, John F. K.
Australian Journal of Chemistry, 1980 , vol. 33, # 4 p. 843 - 852