4-氯-6-甲氧基-2-苯基喹啉合成路线 （共 14 条）
反应条件
1: 78 percent / K2CO3 / dimethylformamide / 3 h / 140 °C
2: 82 percent / diphenyl ether / 1 h / 230 - 250 °C
3: 85 percent / NaOH / ethanol / 6 h / Heating
4: 92 percent / POCl3 / Heating
View Scheme
参考文献
Zhao, Yue-Ling; Chen, Yeh-Long; Chang, Feng-Shuo; Tzeng, Cherng-Chyi
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 8 p. 792 - 797
反应条件
1: 78 percent / K2CO3 / dimethylformamide / 3 h / 140 °C
2: 82 percent / diphenyl ether / 1 h / 230 - 250 °C
3: 85 percent / NaOH / ethanol / 6 h / Heating
4: 92 percent / POCl3 / Heating
View Scheme
参考文献
Zhao, Yue-Ling; Chen, Yeh-Long; Chang, Feng-Shuo; Tzeng, Cherng-Chyi
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 8 p. 792 - 797
反应条件
hydrogenchloride; KNO2; water
参考文献
John
Journal fuer Praktische Chemie (Leipzig), 1931 , vol. <2> 130, p. 293,295
反应条件
1: acetic anhydride, sulphuric acid
2: phosphorous oxychloride / Heating
View Scheme
参考文献
Desai; Desai, Pratibha; Machhi, Dilip; Patel, Dinesh
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 8 p. 871 - 873
