(±)-反-1,2-环戊二醇合成路线 （共 48 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C;
参考文献
Dang; Roberts; Tocher
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 19 p. 2452 - 2461
反应条件
ueber das Strychnin-Salz des Disulfo-Derivats;
参考文献
Bortolini, Olga; Casanova, Elena; Fantin, Giancarlo; Medici, Alessandro; Poli, Silvia; Hanau, Stefania
Tetrahedron Asymmetry, 1998 , vol. 9, # 4 p. 647 - 651
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe in toluene T=-20°C; 9 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Hrdina, Radim; Mueller, Christian E.; Wende, Raffael C.; Wanka, Lukas; Schreiner, Peter R.
Chemical Communications, 2012 , vol. 48, # 19 p. 2498 - 2500
反应条件
N-ethyl-N,N-diisopropylamine; (9S)-6'-methoxycinchonan-9-yl diphenylphosphinite in various solvent(s) T=-78°C; 1 h; Title compound not separated from byproducts;
参考文献
Mizuta, Shinya; Ohtsubo, Yutaka; Tsuzuki, Takeo; Fujimoto, Tetsuya; Yamamoto, Iwao
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8227 - 8229
反应条件
N-ethyl-N,N-diisopropylamine; (9S)-6'-methoxycinchonan-9-yl diphenylphosphinite in various solvent(s) T=-78°C; 1 h; Title compound not separated from byproducts;
参考文献
Mizuta, Shinya; Ohtsubo, Yutaka; Tsuzuki, Takeo; Fujimoto, Tetsuya; Yamamoto, Iwao
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8227 - 8229
反应条件
cyclic dioldehydrogenase from Rhodococcus sp. Moj-3449 in aq. buffer T=30°C; pH=8; 8 h; Enzymatic reaction; enantioselective reaction;
参考文献
Zhang, Jiandong; Xu, Tingting; Li, Zhi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3147 - 3153
反应条件
1: (+/-)-trans-cyclopentane-1,2-diol With (5aS,10bR)-9-nitro-2-phenyl-4,5a,6,10b-tetrahydroindeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-2-ium tetrafluoroborate; 4-(N,N-dimethylamino)benzoic acid; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in chloroform T=20°C; 0.166667 h; 2: 2-bromo-3-phenylpropanal in chloroform T=0°C; 14 h;
参考文献
Kuwano, Satoru; Harada, Shingo; Kang, Bubwoong; Oriez, Raphael; Yamaoka, Yousuke; Takasu, Kiyosei; Yamada, Ken-Ichi
Journal of the American Chemical Society, 2013 , vol. 135, # 31 p. 11485 - 11488
反应条件
C43H60N6O8; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 24 h; Inert atmosphere; enantioselective reaction;
参考文献
Hofmann, Christine; Schuler, Soeren M. M.; Wende, Raffael C.; Schreiner, Peter R.
Chemical Communications, 2014 , vol. 50, # 10 p. 1221 - 1223
反应条件
sodium hydroxide; p-toluenesulfonyl chloride; phenylmethyltriethylammonium bromide in dichloromethane T=25°C; 0.166667 h;
参考文献
Szeja, W.
Synthesis, 1985 , # 10 p. 983 - 985
反应条件
sodium carbonate in ethyl acetate T=20°C; 14 h;
参考文献
Bodai, Viktoria; Orovecz, Oliver; Szakacs, Gyoergy; Novak, Lajos; Poppe, Laszlo
Tetrahedron Asymmetry, 2003 , vol. 14, # 17 p. 2605 - 2612
