1-甲基-4-(4-氯苯基)-1,2,3,6-四氢吡啶合成路线 （共 5 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
10 h; Heating; Yield given;
参考文献
Gessner, Wieslaw; Brossi, Arnold; Shen, Rong-sen; Abell, Creed W.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 3 p. 311 - 317
反应条件
1: tetrahydrofuran / -78 °C
2: HCl, acetic acid / Heating
View Scheme
参考文献
Mabic, Stephane; Castagnoli Jr., Neal
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3694 - 3700
反应条件
1: tetrahydrofuran / -78 °C
2: HCl, acetic acid / Heating
View Scheme
参考文献
Mabic, Stephane; Castagnoli Jr., Neal
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3694 - 3700
反应条件
1: potassium carbonate / acetone / 14 h / Heating
2: LiAlH4 / tetrahydrofuran / 10 h / Heating
View Scheme
参考文献
Gessner, Wieslaw; Brossi, Arnold; Shen, Rong-sen; Abell, Creed W.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 3 p. 311 - 317
反应条件
hydrogenchloride; acetic acid
Heating;
参考文献
Mabic, Stephane; Castagnoli Jr., Neal
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3694 - 3700
