4,4-二甲基-5-(对甲苯)-1,1:3,1-ter苯基合成路线 （共 26 条）
反应条件
nitric acid T=160 - 180°C; im geschlossenen Rohr;
参考文献
Kothe,G.; Zimmermann,H.
Tetrahedron, 1973 , vol. 29, p. 2305 - 2313
反应条件
TiCl3(OTf)
T=90 - 100°C; 10 h;
参考文献
Iranpoor; Zeynizaded
Synlett, 1998 , # 10 p. 1079 - 1080
反应条件
carbon dioxide; copper dichloride; palladium dichloride in water
T=20°C; P=7500.6 Torr; 24 h;
参考文献
Li, Jin-Heng; Xie, Ye-Xiang
Synthetic Communications, 2004 , vol. 34, # 9 p. 1737 - 1743
反应条件
bis(cyclopentadienyl)titanium dichloride; C14H10Mg(THF)3 in benzene-d6
T=75°C; 2 h; Product distribution;
参考文献
Ladipo, Folami T.; Sarveswaran, Vallipuram; Kingston, Jesudoss V.; Huyck, Rebecca A.; Bylikin; Carr, Shana D.; Watts, Randy; Parkin, Sean
Journal of Organometallic Chemistry, 2004 , vol. 689, # 3 p. 502 - 514
反应条件
Ni(Cl){2-(Ph2P)C6H4NCH(Ph)P(O)Ph2} in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=25°C; Negishi coupling reaction; 12 h; Inert atmosphere;
参考文献
Liu, Ning; Wang, Li; Wang, Zhong-Xia
Chemical Communications, 2011 , vol. 47, # 5 p. 1598 - 1600
反应条件
1-[2-(diphenylphosphino)phenyl]ethanol; bis(acetylacetonate)nickel(II) in diethyl ether
T=20°C; 2 h;
参考文献
THE UNIVERSITY OF TOKYO
Patent: WO2006/85628 A1, 2006 ;
Location in patent: Page/Page column 34-35 ;
反应条件
potassium carbonate in ethanol; water
T=20°C; Suzuki-Miyaura coupling; 10 h;
参考文献
Sreedhar; Yada, Divya; Reddy, P. Surendra
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 14-15 p. 2823 - 2836
反应条件
toluene-4-sulfonic acid in neat (no solvent)
T=60 - 140°C; 14 h; Green chemistry; regioselective reaction;
参考文献
Gao, Qi; Bao, Fang-Ping; Feng, Xiao-Jing; Pan, Ying-Ming; Wang, Heng-Shan; Li, Dian-Peng
Arkivoc, 2013 , vol. 2013, # 3 p. 49 - 60
反应条件
Cp2Zr(OSO2C8H17)2 in toluene
T=110°C; 3.5 h; chemoselective reaction;
参考文献
Zhang, Guo Ping; Qiu, Ren Hua; Xu, Xin Hua; Zhou, Hai Hui; Kuang, Ya Fei; Chen, Si Hai
Synthetic Communications, 2012 , vol. 42, # 6 p. 858 - 864
反应条件
1: 1,2,4-trifluorobenzene; p-MeC6H4ZnCl With Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=25 - 100°C; 10 h; Schlenk techniqueInert atmosphere;
2: p-MeC6H4ZnCl in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=100°C; 10 h; Inert atmosphereSchlenk technique;
参考文献
Zhu, Feng; Wang, Zhong-Xia
Journal of Organic Chemistry, 2014 , vol. 79, # 10 p. 4285 - 4292
