6-甲氧基-2-萘酸甲酯合成路线 （共 14 条）
反应条件
[Ni0(1,5-cyclooctadiene)2]; methyl dimethoxy silane; tri-cyclo-hexyl-phosphine in toluene T=80°C; 12 h; Inert atmosphere;
参考文献
Tobisu, Mamoru; Yamakawa, Ken; Shimasaki, Toshiaki; Chatani, Naoto
Chemical Communications, 2011 , vol. 47, # 10 p. 2946 - 2948
反应条件
lithium hydroxide in tetrahydrofuran Heating;
参考文献
Berglund, Magnus; Dalence-Guzman, Maria F.; Skogvall, Staffan; Sterner, Olov
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 5 p. 2529 - 2540
反应条件
sulfuric acid
T=80°C; 8 h;
参考文献
SIENA BIOTECH S.P.A.; WYETH PHARMACEUTICALS
Patent: WO2007/98826 A2, 2007 ;
Location in patent: Page/Page column 76 ;
WO 2007/098826 A2
反应条件
dimethyl sulfate in sodium hydroxide
参考文献
Bayer Aktiengesellschaft
Patent: US5763641 A1, 1998 ;
反应条件
in methanol; hexane; benzene
T=0°C; 1 h;
参考文献
Wyeth
Patent: US2004/127570 A1, 2004 ;
Location in patent: Page/Page column 6 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
Berglund, Magnus; Dalence-Guzman, Maria F.; Skogvall, Staffan; Sterner, Olov
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 5 p. 2529 - 2540
反应条件
potassium carbonate in acetone
2.5 h; Heating / refluxNitrogen atmosphere;
参考文献
CORTICAL PTY LTD
Patent: WO2003/104178 A1, 2003 ;
Location in patent: Page 87 ;
反应条件
ammonium cerium(IV) nitrate; dilithium tetrachloropalladate
T=25°C; 24 h;
参考文献
Cho, Chan Sik; Tanabe, Koichiro; Itoh, Osamu; Uemura, Sakae
Journal of Organic Chemistry, 1995 , vol. 60, # 1 p. 274 - 275
反应条件
sulfuric acid
Heating;
参考文献
Haydock; Mulholland; Telford; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 3 p. 205 - 214
反应条件
1: 80 percent / NaOCl, HCl / H2O; ethanol
2: 85 percent / H2SO4 / Heating
View Scheme
参考文献
Haydock; Mulholland; Telford; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 3 p. 205 - 214
