sodium hydride in tetrahydrofuran T=0 - 20°C; Wadsworth-Horner-Emmons olefination; 2 h;

1: With pyridine; thionyl chloride in diethyl ether T=20°C; 48 h; 2: With sodium hydroxide in ethanol; water T=30°C; 0.333333 h; Further stages.;

1.1: 95 percent / Zn; iodine / benzene / 2.5 h / Heating 2.1: SOCl2; pyridine / diethyl ether / 48 h / 20 °C 2.2: 11 percent / NaOH / H2O; ethanol / 0.33 h / 30 °C View Scheme

1.1: 95 percent / Zn; iodine / benzene / 2.5 h / Heating 2.1: SOCl2; pyridine / diethyl ether / 48 h / 20 °C 2.2: 11 percent / NaOH / H2O; ethanol / 0.33 h / 30 °C View Scheme