3,5-吡啶二甲酸 3-甲酯合成路线 (共 3 条)
反应条件
potassium hydroxide in methanol T=20°C; 12 h;
参考文献
Broadus, Katherine M.; Kass, Steven R.
Journal of the American Chemical Society, 2000 , vol. 122, # 37 p. 9014 - 9018
反应条件
1: With thionyl chloride T=0 - 50°C; 2: With potassium hydrogencarbonate in methanol; water T=20°C; 3: With hydrogenchloride in methanol; water pH=3;
参考文献
Boehringer Ingelheim International GmbH
Patent: US2006/223759 A1, 2006 ;
Location in patent: Page/Page column 191-192 ;
参考文献
Cilag
Patent: US2654759 , 1951 ;