4,6-二氯-5-甲氧基嘧啶合成路线 （共 4 条）
反应条件
triethylamine; trichlorophosphate in toluene T=100 - 105°C; 1.5 h; Reflux;
参考文献
ARENA PHARMACEUTICALS, INC.
Patent: US2009/286816 A1, 2009 ;
Location in patent: Page/Page column 12 ;
反应条件
hydrogenchloride in water; acetonitrile
参考文献
Fabre-Kramer Pharmaceuticals, Inc.
Patent: US2009/281114 A1, 2009 ;
US 20090281114 A1
反应条件
hydrogenchloride in water; acetonitrile
参考文献
Fabre-Kramer Pharmaceuticals, Inc.
Patent: US2009/281114 A1, 2009 ;
US 20090281114 A1
反应条件
ammonia in water; butan-1-ol T=90°C; 2.5 h;
参考文献
MERCK SHARP and DOHME LIMITED
Patent: WO2005/47279 A1, 2005 ;
Location in patent: Page/Page column 33 ;
WO 2005/047279 A1
