4-(叔丁氧基羰基氨基)-1-甲基-1H-咪唑-2-羧酸甲酯合成路线 （共 6 条）
反应条件
potassium tert-butylate; water in tetrahydrofuran T=20°C; 1 h;
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
反应条件
trifluoroacetic acid in dichloromethane; water 1 h;
参考文献
Taleb, Robin I.; Jaramillo, David; Wheate, Niai J.; Aldrich-Wright, Janice R.
Chemistry - A European Journal, 2007 , vol. 13, # 11 p. 3177 - 3186
反应条件
hydrogen; palladium on activated charcoal in methanol
31 h;
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
参考文献
Pharmacia Corporation
Patent: US2003/80320 A1, 2003 ;
反应条件
1: 70 percent / methanol / 3 h
2: 91 percent / hydrogen / Pd/C / methanol / 31 h
View Scheme
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
反应条件
1: 65 percent / HNO3; H2SO4; acetic anydride / 24 h / 0 - 20 °C
2: 70 percent / methanol / 3 h
3: 91 percent / hydrogen / Pd/C / methanol / 31 h
View Scheme
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
