1-(4'-氯-联苯-4-基)-乙酮合成路线 （共 25 条）
参考文献
Musante; Parrini
Gazzetta Chimica Italiana, 1950 , vol. 80, p. 868,879
反应条件
cesium fluoride in water; N,N-dimethyl-formamide
T=95°C; Suzuki-Miyaura reaction; 2 h;
参考文献
Hoshiya, Naoyuki; Shimoda, Masahiko; Yoshikawa, Hideki; Yamashita, Yoshiyuki; Shuto, Satoshi; Arisawa, Mitsuhiro
Journal of the American Chemical Society, 2010 , vol. 132, # 21 p. 7270 - 7272
反应条件
aluminium trichloride; nitrobenzene
T=10 - 15°C;
参考文献
Mowry; Renoll; Huber
Journal of the American Chemical Society, 1946 , vol. 68, p. 1105,1107
反应条件
1: 4'-iodoacetophenone in N,N-dimethyl-formamide
T=90°C; 0.833333 h; Microwave irradiation;
2: (4-Chlorophenyl)-boronic acid With potassium carbonate in N,N-dimethyl-formamide
T=102°C; Suzuki-Miyaura Coupling; 1 h; Microwave irradiation;
参考文献
Al-Amin, Mohammad; Akimoto, Masayoshi; Tameno, Tsuyoshi; Ohki, Yuuta; Takahashi, Naoyuki; Hoshiya, Naoyuki; Shuto, Satoshi; Arisawa, Mitsuhiro
Green Chemistry, 2013 , vol. 15, # 5 p. 1142 - 1145
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide
T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Jadhav, Deepak N.
Tetrahedron Letters, 2007 , vol. 48, # 38 p. 6644 - 6647
反应条件
tetrabutyl ammonium fluoride; acetic acid in toluene
T=100°C; Hiyama Coupling; 24 h;
参考文献
Huang, Shao-Hsien; Liu, Chun-Hsia; Yang, Chia-Min
Green Chemistry, 2014 , vol. 16, # 5 p. 2706 - 2712
反应条件
1: 4-chlorophenyl-magnesium bromide With N,N,N',N,-tetramethylethylenediamine; zinc(II) chloride in tetrahydrofuran
T=80°C; 0.25 h; microwave irradiation;
2: para-bromoacetophenone With bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; Negishi cross-coupling; 0.0333333 h; microwave irradiation;
参考文献
Mutule, Ilga; Suna, Edgars
Tetrahedron, 2005 , vol. 61, # 47 p. 11168 - 11176
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide
T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Jadhav, Deepak N.
Tetrahedron Letters, 2007 , vol. 48, # 15 p. 2707 - 2711
反应条件
palladium diacetate in ethanol
T=95°C; 0.25 h; microwave irradiation;
参考文献
Kabalka, George W.; Zhou, Li-Li; Naravane, Abhijit
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6887 - 6889
反应条件
1: hexakis-(4-chloro-phenyl)-cyclotrisiloxane With potassium hydroxide in 1,4-dioxane; water
Heating;
2: para-bromoacetophenone With palladium diacetate in 1,4-dioxane; water
0.5 h; Heating; Further stages.;
参考文献
Endo, Mayuko; Sakurai, Tomoyuki; Ojima, Satoshi; Katayama, Takako; Unno, Masafumi; Matsumoto, Hideyuki; Kowase, Susumu; Sano, Hiroshi; Kosugi, Masanori; Fugami, Keigo
Synlett, 2007 , # 5 p. 749 - 752
