1-乙酰基-5-氨基二氢吲哚合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=2585.81 Torr; 3 h;
参考文献
LUPIN LIMITED
Patent: WO2009/109999 A1, 2009 ;
Location in patent: Page/Page column 77 ;
WO 2009/109999 A1
反应条件
hydrogen; 10 Pd-BaSO4 in ethanol 2 h;
参考文献
AVENTIS PHARMA S.A.
Patent: WO2006/10642 A1, 2006 ;
Location in patent: Page/Page column 76 ;
WO 2006/010642 A1
反应条件
1: 5-nitro-2,3-dihydro-indole; acetic anhydride 2: With hydrogen; palladium on activated charcoal in methanol
参考文献
Laconde; Depreux; Berthelot; Henichart
Heteroatom Chemistry, 2005 , vol. 16, # 1 p. 39 - 43
反应条件
sulfuric acid; hydrogen; nitric acid; platinum 2) EtOH; Multistep reaction;
参考文献
Prasad; Burchat; Weeratunga; Watts; Dmitrienko
Tetrahedron Letters, 1991 , vol. 32, # 38 p. 5035 - 5038
反应条件
1: p-TSA 2: 1) HNO3, H2SO4, 2) H2 / 2) Pt / 2) EtOH View Scheme
参考文献
Prasad; Burchat; Weeratunga; Watts; Dmitrienko
Tetrahedron Letters, 1991 , vol. 32, # 38 p. 5035 - 5038
反应条件
1: 1) Na2CO3, 2) NEt3 / 1) EtOH, 2) hexane
2: 86 percent / TFA, (CF3CO)2O
3: 76 percent / DDQ / benzene / Heating
4: 91 percent / KOH / methanol
View Scheme
参考文献
Prasad; Burchat; Weeratunga; Watts; Dmitrienko
Tetrahedron Letters, 1991 , vol. 32, # 38 p. 5035 - 5038
