2,5-二甲基吡啶 1-氧化物合成路线 (共 11 条)
反应条件
1: CH2Cl2 / 0.42 h / 20 °C
2: 9.72 g / Et2NCOCl / CH2Cl2 / 96 h / 20 °C
3: 57 percent / H2; aq. HCl / Pd/C / 2 h / 1551.44 Torr
View Scheme
参考文献
Russell, Michael G. N.; Carling, Robert W.; Atack, John R.; Bromidge, Frances A.; Cook, Susan M.; Hunt, Peter; Isted, Catherine; Lucas, Matt; McKernan, Ruth M.; Mitchinson, Andrew; Moore, Kevin W.; Narquizian, Robert; Macaulay, Alison J.; Thomas, David; Thompson, Sally-Anne; Wafford, Keith A.; Castro, Jose L.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 5 p. 1367 - 1383