4-(2-硝基乙烯基)吲哚合成路线 （共 5 条）
参考文献
Maryanoff, Bruce E.; McComsey, David F.; Martin, Gregory E.; Shank, Richard P.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 8 p. 983 - 988
反应条件
1: 85 percent / MnO2 2: 95 percent / NH4OAc View Scheme
参考文献
Maryanoff, Bruce E.; McComsey, David F.; Martin, Gregory E.; Shank, Richard P.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 8 p. 983 - 988
反应条件
1: 80 percent / LiAlH4 2: 85 percent / MnO2 3: 95 percent / NH4OAc View Scheme
参考文献
Maryanoff, Bruce E.; McComsey, David F.; Martin, Gregory E.; Shank, Richard P.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 8 p. 983 - 988
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 3 h; Heating / reflux;
参考文献
URQUIMA S.A.
Patent: WO2005/40115 A1, 2005 ;
Location in patent: Page/Page column 4 ;
反应条件
1: 74 percent / sodium borohydride / methanol / 0.5 h
3: 88 percent / sodium borohydride / methanol / 0.33 h
4: 1.) sodium methoxide, 2.) aq. 20percent titanium trichloride, aq. ammonium acetate / 1.) methanol, 5 min, 2.) room temperature, 45 min
5: 49 percent / sodium cyanoborohydride, dimethylamine hydrochloride / methanol / 2 h / Ambient temperature
View Scheme
参考文献
Kruse; Meyer
Journal of Organic Chemistry, 1984 , vol. 49, # 25 p. 4761 - 4768
