(Z)-1-羟基-10-十六碳烯-7-酮合成路线 （共 9 条）
反应条件
hydrogenchloride in acetone
48 h;
参考文献
Odinokov, V. N.; Botsman, L. P.; Nagaeva, N. A.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 68 - 70
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 1 p. 80 - 83
反应条件
1: 90 percent / H2, quinoline / lindlar catalyst / hexane
2: 75 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature
3: 1.) Mg / 1.) THF, RT, 1 h, 2.) overnight
4: 66.1 percent / pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1 h / Ambient temperature
5: 78.1 percent / PTS / methanol / 6 h / Ambient temperature
View Scheme
参考文献
Vig; Sharma; Walia; Thaper
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 8 p. 760 - 762
反应条件
1: 71 percent / tetrahydrofuran / 0.5 h at 0 deg C, then 3 h at 25 deg C
2: 90 percent / CrO3*Py*HCl / CH2Cl2 / 2 h
3: 90 percent / 5percent HCl / acetone / 48 h
View Scheme
参考文献
Odinokov, V. N.; Botsman, L. P.; Nagaeva, N. A.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 68 - 70
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 1 p. 80 - 83
反应条件
1: 90 percent / CrO3*Py*HCl / CH2Cl2 / 2 h
2: 90 percent / 5percent HCl / acetone / 48 h
View Scheme
参考文献
Odinokov, V. N.; Botsman, L. P.; Nagaeva, N. A.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 68 - 70
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 1 p. 80 - 83
反应条件
1: 71 percent / tetrahydrofuran / 0.5 h at 0 deg C, then 3 h at 25 deg C
2: 90 percent / CrO3*Py*HCl / CH2Cl2 / 2 h
3: 90 percent / 5percent HCl / acetone / 48 h
View Scheme
参考文献
Odinokov, V. N.; Botsman, L. P.; Nagaeva, N. A.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 68 - 70
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 1 p. 80 - 83
反应条件
1: 90 percent / CuI / diethyl ether
2: 95 percent / 5percent HCl / acetone / 4 h / Ambient temperature
3: 71 percent / tetrahydrofuran / 0.5 h at 0 deg C, then 3 h at 25 deg C
4: 90 percent / CrO3*Py*HCl / CH2Cl2 / 2 h
5: 90 percent / 5percent HCl / acetone / 48 h
View Scheme
参考文献
Odinokov, V. N.; Botsman, L. P.; Nagaeva, N. A.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 68 - 70
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 1 p. 80 - 83
反应条件
1: 95 percent / 5percent HCl / acetone / 4 h / Ambient temperature
2: 71 percent / tetrahydrofuran / 0.5 h at 0 deg C, then 3 h at 25 deg C
3: 90 percent / CrO3*Py*HCl / CH2Cl2 / 2 h
4: 90 percent / 5percent HCl / acetone / 48 h
View Scheme
参考文献
Odinokov, V. N.; Botsman, L. P.; Nagaeva, N. A.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 68 - 70
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 1 p. 80 - 83
反应条件
1: 1.) Mg / 1.) THF, RT, 1 h, 2.) overnight
2: 66.1 percent / pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1 h / Ambient temperature
3: 78.1 percent / PTS / methanol / 6 h / Ambient temperature
View Scheme
参考文献
Vig; Sharma; Walia; Thaper
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 8 p. 760 - 762
反应条件
1: 75 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature
2: 1.) Mg / 1.) THF, RT, 1 h, 2.) overnight
3: 66.1 percent / pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1 h / Ambient temperature
4: 78.1 percent / PTS / methanol / 6 h / Ambient temperature
View Scheme
参考文献
Vig; Sharma; Walia; Thaper
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 8 p. 760 - 762
