1,2,5,6-四氢吡啶-3-羧酸盐酸盐合成路线 （共 18 条）
反应条件
hydrogenchloride T=180 - 200°C;
参考文献
McElvain; Stork
Journal of the American Chemical Society, 1946 , vol. 68, p. 1049,1052
反应条件
barium dihydroxide in water T=40°C; 0.5 h;
参考文献
Wolf-Pflugmann; Lambrecht; Wess; Mutschler
Arzneimittel-Forschung/Drug Research, 1989 , vol. 39, # 5 p. 539 - 544
反应条件
1: benzene 2: sodium; ethanol; benzene 3: Raney nickel; ethanol / 120 °C / 128714 Torr / Hydrogenation 4: HCl / 180 - 200 °C View Scheme
参考文献
McElvain; Stork
Journal of the American Chemical Society, 1946 , vol. 68, p. 1049,1052
反应条件
1: sodium; ethanol; benzene 2: Raney nickel; ethanol / 120 °C / 128714 Torr / Hydrogenation 3: HCl / 180 - 200 °C View Scheme
参考文献
McElvain; Stork
Journal of the American Chemical Society, 1946 , vol. 68, p. 1049,1052
反应条件
1: Raney nickel; ethanol / 120 °C / 128714 Torr / Hydrogenation 2: HCl / 180 - 200 °C View Scheme
参考文献
McElvain; Stork
Journal of the American Chemical Society, 1946 , vol. 68, p. 1049,1052
反应条件
in water 3 h; Reflux;
参考文献
Song, Song; Zhu, Shou-Fei; Pu, Liu-Yang; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 23 p. 6072 - 6075
Angew. Chem., 2013 , vol. 125, # 23 p. 6188 - 6191
反应条件
1: toluene 2: water / Ambient temperature 3: Ba(OH)2*8H2O / H2O / 0.5 h / 40 °C View Scheme
参考文献
Song, Song; Zhu, Shou-Fei; Pu, Liu-Yang; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 23 p. 6072 - 6075
Angew. Chem., 2013 , vol. 125, # 23 p. 6188 - 6191
反应条件
1: water / Ambient temperature 2: Ba(OH)2*8H2O / H2O / 0.5 h / 40 °C View Scheme
参考文献
Wolf-Pflugmann; Lambrecht; Wess; Mutschler
Arzneimittel-Forschung/Drug Research, 1989 , vol. 39, # 5 p. 539 - 544
反应条件
sulfuric acid Electrolysis;
参考文献
Sorm
Collection of Czechoslovak Chemical Communications, 1948 , vol. 13, p. 57,68
参考文献
Ferles; Prystas
Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 3326,3332
