3-氨基-4-甲氧基苯磺酰基氟合成路线 （共 5 条）
反应条件
hydrogenchloride; tin T=45 - 50°C;
参考文献
Steinkopf
Journal fuer Praktische Chemie (Leipzig), 1927 , vol. <2> 117, p. 21
反应条件
1: HNO3+H2SO4 / 6 - 8 °C 2: tin; concentrated hydrochloric acid / 45 - 50 °C View Scheme
参考文献
Steinkopf
Journal fuer Praktische Chemie (Leipzig), 1927 , vol. <2> 117, p. 21
反应条件
ammonium hydroxide in water
T=0 - 50°C;
参考文献
JACKSON, Paul Francis; Tounge, Brett Andrew; Leonard, Kristi Anne; Zhang, Yan; Wang, Aihua; Hawkins, Michael; Maharoof, Umar S.M.; Barbay, Joseph Kent
Patent: US2012/129842 A1, 2012 ;
Location in patent: Page/Page column 58 ;
反应条件
pyridine
T=20°C; 4 h;
参考文献
Bayer Pharmaceuticals Corp.
Patent: EP1042305 B1, 2005 ;
Location in patent: Page/Page column 19 ;
反应条件
acetic anhydride in pyridine; dichloromethane
参考文献
BAYER CORPORATION
Patent: US2004/102636 A1, 2004 ;
US 20040102636 A1
