反应条件
1: 92 percent / toluensulphonic acid / benzene / 4 h / Heating
2: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2.) -78 deg C -> -22 deg C, 2 h
3: 99 percent / pyridine / 40 h / 6 °C
4: chloramine-T / tetrahydrofuran / 1 h
5: 2,6-di-tert-butylpyridine, NaI / acetone / 17.5 h / 54 °C
6: 1.) LDA / 1.) DME, -78 deg C, 12 min, 2.) -78 deg C, 2 h
7: 1.) LDA / 1.) DME, -78 deg C, 10 min, 2.) -78 deg C -> 0 deg C, 25 min
8: 1.) m-CPBA, 2.) pyridine, 3.) Me2S, 4.) PhSH, NEt3
9: 88 percent / AcOH / tetrahydrofuran; H2O / 7 h / 21 °C
View Scheme
参考文献
Reich, Hans J.; Shah, Shrenik K.; Gold Paul M.; Olson Richard E.
Journal of the American Chemical Society, 1981 , vol. 103, # 11 p. 3112 - 3120
