1,4-二氧杂螺[4.5]癸烷-9-酮合成路线 （共 12 条）
反应条件
sulfuric acid; silica gel in dichloromethane 6 h; Ambient temperature;
参考文献
Bhushan, Vidya; Chandrasekaran, S.
Synthetic Communications, 1984 , vol. 14, # 4 p. 339 - 346
反应条件
1: Raney nickel; ethanol / unter Druck 2: HCl; water View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 3331
反应条件
toluene-4-sulfonic acid in benzene
1.5 h; Heating;
参考文献
Morlender-Vais; Mandelbaum
Journal of Mass Spectrometry, 1998 , vol. 33, # 3 p. 229 - 241
反应条件
pyridine; Catalyst M-Chromium oxide; kieselguhr in dichloromethane
0.333333 h; Ambient temperature;
参考文献
Vankar, Yashwant D.; Chaudhuri, Narayan C.; Rao, C. Trinadha
Tetrahedron Letters, 1987 , vol. 28, # 5 p. 551 - 554
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
4 h; Heating;
参考文献
Vankar, Yashwant D.; Reddy, M. Venkatram; Chaudhuri, Narayan C.
Tetrahedron, 1994 , vol. 50, # 37 p. 11057 - 11078
反应条件
1: 89 percent / N-bromosuccinimide / dimethylsulfoxide; H2O / 10 °C
2: 65 percent / pyridine, chromium trioxide, celite / CH2Cl2 / 20 - 25 °C
3: 81 percent / tributyltinhydride, AIBN / benzene / 4 h / Heating
View Scheme
参考文献
Vankar, Yashwant D.; Reddy, M. Venkatram; Chaudhuri, Narayan C.
Tetrahedron, 1994 , vol. 50, # 37 p. 11057 - 11078
反应条件
toluene-4-sulfonic acid; ethylene glycol; benzene
参考文献
Cronyn; Goodrich
Journal of the American Chemical Society, 1952 , vol. 74, p. 3331
反应条件
1: 65 percent / pyridine, chromium trioxide, celite / CH2Cl2 / 20 - 25 °C
2: 81 percent / tributyltinhydride, AIBN / benzene / 4 h / Heating
View Scheme
参考文献
Vankar, Yashwant D.; Reddy, M. Venkatram; Chaudhuri, Narayan C.
Tetrahedron, 1994 , vol. 50, # 37 p. 11057 - 11078
反应条件
1: 86 percent / LiAlH4 / tetrahydrofuran / 24 h / Heating
2: 90 percent / pyridine, Cr2O3, kieselguhr / CH2Cl2 / 0.33 h / Ambient temperature
View Scheme
参考文献
Vankar, Yashwant D.; Chaudhuri, Narayan C.; Rao, C. Trinadha
Tetrahedron Letters, 1987 , vol. 28, # 5 p. 551 - 554
反应条件
1: 80 percent / potassium tert-butoxide / dimethylsulfoxide
2: 1.) aq. mercuric acetate, 2.) aq. sodium hydroxide, sodium borohydride / 1.) THF, 30 deg C, 3 h, 2.) 0 deg C, 1 h
3: 86 percent / chromium trioxide-pyridine / CH2Cl2
View Scheme
参考文献
Bhushan, Vidya; Chandrasekaran, S.
Synthetic Communications, 1984 , vol. 14, # 4 p. 339 - 346
