1-甲基-1,2,3,4-四氢异喹啉合成路线 （共 44 条）
反应条件
1.1: n-BuLi / hexane; 1,2-dimethoxy-ethane / 1 h / -35 °C 1.2: 55 percent / hexane; 1,2-dimethoxy-ethane / 18 h 2.1: 74 percent / In; aq. NH4Cl / ethanol / Heating View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 9 p. 955 - 977
反应条件
1: 1) tBuLi/hexamethylphosphorsaeuretriamide / 1) THF, -80 deg C, 5min 2: 71 percent / KOH / methanol View Scheme
参考文献
Angewandte Chemie, , vol. 93, # 1 p. 125 - 126
反应条件
2: 1) tBuLi/hexamethylphosphorsaeuretriamide / 1) THF, -80 deg C, 5min 3: 71 percent / KOH / methanol View Scheme
参考文献
Angewandte Chemie, , vol. 93, # 1 p. 125 - 126
反应条件
1: 1) n-BuLi / 1) THF, -78 deg C, 1 h; 2) room temp. 2: 93 percent / 2.0 M HCl / 4 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 39, # 12 p. 1963 - 1974
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 42, # 9 p. 2571 - 2574
参考文献
Heterocycles, , vol. 19, # 4 p. 653 - 656
反应条件
C21H21ClIrNO2 in tetrahydrofuran; 2,2,2-trifluoroethanol 20 h; Inert atmosphere;
参考文献
Wu, Jianjun; Talwar, Dinesh; Johnston, Steven; Yan, Ming; Xiao, Jianliang
Angewandte Chemie - International Edition, 2013 , vol. 52, # 27 p. 6983 - 6987
Ross. Khim. Zh., 2013 , vol. 125, # 27 p. 7121 - 7125,5
反应条件
C21H21ClIrNO2 in 2,2,2-trifluoroethanol 3 h; RefluxInert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 27 p. 6983 - 6987
Ross. Khim. Zh., , vol. 125, # 27 p. 7121 - 7125,5
反应条件
Candida rugosa lipase in di-isopropyl ether T=30°C; 48 h;
参考文献
Breen, Gary F.
Tetrahedron Asymmetry, 2004 , vol. 15, # 9 p. 1427 - 1430
反应条件
T=100°C; 0.5 h; Yield given. Title compound not separated from byproducts;
参考文献
Potapov, V. M.; Dem'yanovich, V. M.; Krivdin, L. B.; Skvortsova, T. V.; Bkhatti, Z. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 5 p. 486 - 489
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , # 5 p. 662 - 665
