5-甲氧基-1,3-苯并噁唑-2-硫醇合成路线 (共 6 条)
参考文献
FIBROGEN, INC.
Patent: WO2007/90068 A2, 2007 ;
Location in patent: Page/Page column 86 ;
反应条件
potassium hydroxide in methanol; water
参考文献
Zeneca Limited
Patent: US5451681 A1, 1995 ;
反应条件
1: H2 / Pd-C / ethanol 2: KOH / ethanol / Heating View Scheme
参考文献
Ramurthy, Savithri; Aikawa, Mina; Amiri, Payman; Costales, Abran; Hashash, Ahmad; Jansen, Johanna M.; Lin, Song; Ma, Sylvia; Renhowe, Paul A.; Shafer, Cynthia M.; Subramanian, Sharadha; Sung, Leonard; Verhagen, Joelle
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3286 - 3289
反应条件
potassium hydroxide in methanol; water
参考文献
Yoshida, Satoshi; Watanabe, Takashi; Sato, Yasuo
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 10 p. 3515 - 3523
反应条件
in ethanol 6 h; Heating;
参考文献
Evangelista, S.; Ghelardoni, M.; Meli, A.; Pestellini, V.; Viti, G.
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 11 p. 901 - 908
反应条件
thionyl chloride in N,N-dimethyl-formamide
T=80°C; 0.5 h;
参考文献
Ramurthy, Savithri; Aikawa, Mina; Amiri, Payman; Costales, Abran; Hashash, Ahmad; Jansen, Johanna M.; Lin, Song; Ma, Sylvia; Renhowe, Paul A.; Shafer, Cynthia M.; Subramanian, Sharadha; Sung, Leonard; Verhagen, Joelle
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3286 - 3289