1-苯基-2-丁烯-1-酮合成路线 （共 117 条）
反应条件
1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 0.33 h / 20 °C 2: bis(1,1-diphenylphosphino)methane; tetracarbonylbis(μ-chloro)dirhodium(I) / ethylene glycol dimethyl ether / 20 h / 65 °C / |Inert atmosphere View Scheme
参考文献
Zhuo, Lian-Gang; Yao, Zhong-Ke; Yu, Zhi-Xiang
Organic Letters, 2013 , vol. 15, # 18 p. 4634 - 4637
反应条件
potassium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=80°C; Yield given. Yields of byproduct given;
参考文献
Snowden, Roger L.; Linder, Simon M.; Muller, Bernard L.; Schulte, Karl H.
Helvetica Chimica Acta, 1987 , vol. 70, p. 1858 - 1878
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tris(4-methylphenyl)-phosphine in 1,3,5-trimethyl-benzene T=150°C; 12 h; Inert atmosphere;
参考文献
Rodriguez, Nuria; Manjolinho, Filipe; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13688 - 13691
反应条件
1.1: Mg / tetrahydrofuran 1.2: 78 percent / tetrahydrofuran 2.1: 88 percent / MnO2 / diethyl ether / 2 h / 20 °C View Scheme
参考文献
Onishi, Yoshiharu; Yoneda, Yuki; Nishimoto, Yoshihiro; Yasuda, Makoto; Baba, Akio
Organic Letters, 2012 , vol. 14, # 22 p. 5788 - 5791
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tris(4-methylphenyl)-phosphine in toluene T=100°C; 0.5 h; Inert atmosphere;
参考文献
Rodriguez, Nuria; Manjolinho, Filipe; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13688 - 13691
反应条件
1: tetrahydrofuran / 0.5 h / 0 °C 2: pyridinium dichromate / dimethylformamide / 1 h / 20 °C View Scheme
参考文献
Brown, Catherine D.; Chong, J. Michael; Shen, Lixin
Tetrahedron, 1999 , vol. 55, # 50 p. 14233 - 14242
反应条件
1: 99 percent / BF3*O(C2H5)2 / CH2Cl2 / 1 h / 0 °C 2: silica gel View Scheme
参考文献
Curran, Dennis P.; Kim, Byeang Hyean
Synthesis, 1986 , # 4 p. 312 - 315
反应条件
1: 87 percent / Mg / tetrahydrofuran 2: 1) NaH / 1) hexamethylphosphoric triamide, 20 deg C 2) 80 deg C, 2 h View Scheme
参考文献
Snowden, Roger L.; Linder, Simon M.; Muller, Bernard L.; Schulte, Karl H.
Helvetica Chimica Acta, 1987 , vol. 70, p. 1858 - 1878
反应条件
[PtCl2(PhCN)2] in toluene 1.16667 h; Heating; Yield given. Yields of byproduct given;
参考文献
Doyle, Michael P.; Leusen, Daan van
Journal of Organic Chemistry, 1982 , vol. 47, # 27 p. 5326 - 5339
反应条件
triethylamine in tetrahydrofuran
参考文献
Nozaki,H. et al.
Tetrahedron, 1968 , vol. 24, p. 6563 - 6572
