3,4-二氢-2-苯基-2H-1-苯并吡喃合成路线 （共 44 条）
反应条件
1: 0.953 g / NaBH4 / CHCl3; propan-2-ol / 4 h / 20 °C
2: 83 percent / trifluoromethanesulfonic acid / CHCl3 / 0.5 h / 50 °C
3: 69 percent / toluene / 12 h / 120 °C
View Scheme
参考文献
Sugimoto, Hiromichi; Nakamura, Satoshi; Ohwada, Tomohiko
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 4-5 p. 669 - 679
反应条件
1.1: lithium powder; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 1.5 h / 0 °C
1.2: 70 percent / tetrahydrofuran / 0.25 h / -78 °C
2.1: 95 percent / phosphoric acid / toluene; H2O / 4 h / 110 °C
View Scheme
参考文献
Yus, Miguel; Foubelo, Francisco; Ferrandez, Jose V; Bachki, Abderrazak
Tetrahedron, 2002 , vol. 58, # 24 p. 4907 - 4915
反应条件
1: 40 mg / tri-n-butyltin hydride / benzene / 4 h / Heating
2: 0.76 g / aluminium chloride, lithium aluminium hydride / tetrahydrofuran; diethyl ether / 0.33 h / 0 °C
3: 70 mg / aluminium chloride / 2 h
4: sodium cyanoborohydride, acetic acid / acetic anhydride / 2 h
View Scheme
参考文献
Bird, T. Geoffrey C.; Brown, Ben R.; Stuart, Ian A.; Tyrrell, William R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1831 - 1846
反应条件
1: 70 mg / aluminium chloride / 2 h
2: sodium cyanoborohydride, acetic acid / acetic anhydride / 2 h
View Scheme
参考文献
Bird, T. Geoffrey C.; Brown, Ben R.; Stuart, Ian A.; Tyrrell, William R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1831 - 1846
反应条件
1: silver nitrate / 10 h / Heating
2: sodium cyanoborohydride, acetic acid / acetic anhydride / 2 h
View Scheme
参考文献
Bird, T. Geoffrey C.; Brown, Ben R.; Stuart, Ian A.; Tyrrell, William R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1831 - 1846
反应条件
1: 38 mg / Heating
2: 25 mg / aluminium chloride, lithium aluminium hydride / diethyl ether / 12 h / 0 °C
3: silver nitrate / 10 h / Heating
4: sodium cyanoborohydride, acetic acid / acetic anhydride / 2 h
View Scheme
参考文献
Bird, T. Geoffrey C.; Brown, Ben R.; Stuart, Ian A.; Tyrrell, William R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1831 - 1846
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C
1.2: 0 - 20 °C
2.1: sodium tetrahydroborate / ethanol / 0 - 20 °C
3.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 20 °C / Cooling with ice
4.1: p-TsOH immobilized on silica / toluene / 0 - 20 °C
View Scheme
参考文献
Radomkit, Suttipol; Sarnpitak, Pakornwit; Tummatorn, Jumreang; Batsomboon, Paratchata; Ruchirawat, Somsak; Ploypradith, Poonsakdi
Tetrahedron, 2011 , vol. 67, # 21 p. 3904 - 3914
反应条件
1: Heating
2: 25 mg / aluminium chloride, lithium aluminium hydride / diethyl ether / 12 h / 0 °C
3: silver nitrate / 10 h / Heating
4: sodium cyanoborohydride, acetic acid / acetic anhydride / 2 h
View Scheme
参考文献
Bird, T. Geoffrey C.; Brown, Ben R.; Stuart, Ian A.; Tyrrell, William R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1831 - 1846
反应条件
1: 25 mg / aluminium chloride, lithium aluminium hydride / diethyl ether / 12 h / 0 °C
2: silver nitrate / 10 h / Heating
3: sodium cyanoborohydride, acetic acid / acetic anhydride / 2 h
View Scheme
参考文献
Bird, T. Geoffrey C.; Brown, Ben R.; Stuart, Ian A.; Tyrrell, William R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1831 - 1846
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 20 °C / Cooling with ice
2: p-TsOH immobilized on silica / toluene / 0 - 20 °C
View Scheme
参考文献
Radomkit, Suttipol; Sarnpitak, Pakornwit; Tummatorn, Jumreang; Batsomboon, Paratchata; Ruchirawat, Somsak; Ploypradith, Poonsakdi
Tetrahedron, 2011 , vol. 67, # 21 p. 3904 - 3914
