双环[1.1.0]丁烷-1-羧酸甲酯合成路线 （共 9 条）
反应条件
sodium hydroxide; (10H)-phenothiazine; 2,5-di-tert-butyl-1,4-benzoquinone
参考文献
Hall,H.K. et al.
Journal of the American Chemical Society, 1971 , vol. 93, p. 121 - 130
反应条件
2,5-di-tert-butyl-1,4-benzoquinone; sodium hydride in tetrahydrofuran
参考文献
Hall,H.K. et al.
Journal of the American Chemical Society, 1971 , vol. 93, p. 121 - 130
反应条件
1: H2 / Pd / methanol
2: (i) PhSO2Cl, Py, (ii) LiBr, acetone
3: NaH, 4-tert-butyl-benzene-1,2-diol / diethyl ether
View Scheme
参考文献
Wiberg,K.B. et al.
Tetrahedron, 1965 , vol. 21, p. 2749 - 2769
反应条件
1: (i) KOH, aq. EtOH, (ii) (decarboxylation)
2: H2SO4 / 1,2-dichloro-ethane
3: H2 / Pd / methanol
4: (i) PhSO2Cl, Py, (ii) LiBr, acetone
5: NaH, 4-tert-butyl-benzene-1,2-diol / diethyl ether
View Scheme
参考文献
Wiberg,K.B. et al.
Tetrahedron, 1965 , vol. 21, p. 2749 - 2769
反应条件
1: H2SO4 / 1,2-dichloro-ethane
2: H2 / Pd / methanol
3: (i) PhSO2Cl, Py, (ii) LiBr, acetone
4: NaH, 4-tert-butyl-benzene-1,2-diol / diethyl ether
View Scheme
参考文献
Wiberg,K.B. et al.
Tetrahedron, 1965 , vol. 21, p. 2749 - 2769
反应条件
3,4-dihydroxy-1-tert-butylbenzene; sodium hydride in diethyl ether
参考文献
Wiberg,K.B. et al.
Tetrahedron, 1965 , vol. 21, p. 2749 - 2769
反应条件
1: (i) PhSO2Cl, Py, (ii) LiBr, acetone
2: NaH, 4-tert-butyl-benzene-1,2-diol / diethyl ether
View Scheme
参考文献
Wiberg,K.B. et al.
Tetrahedron, 1965 , vol. 21, p. 2749 - 2769
反应条件
potassium tert-butylate in pentane
参考文献
Wiberg,K.B. et al.
Tetrahedron, 1965 , vol. 21, p. 2749 - 2769
参考文献
Chae, Woo-Ki; Baughman, Sharon A.; Engel, Paul S.; Bruch, Manfred; Oezmeral, Cenan; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4824 - 4833
