反应条件
1.1: 100 percent / NBS / dimethylformamide / 24 h / 20 °C
2.1: n-BuLi / tetrahydrofuran; hexane / 1.17 h / -78 °C
2.2: tetrahydrofuran; hexane / -70 - 0 °C
3.1: aq. H2O2 / methanol / 1 h / 20 °C
4.1: t-BuLi / pentane; tetrahydrofuran / 3.5 h / -100 - -70 °C
4.2: I2 / pentane; tetrahydrofuran / 2 h / -70 - 0 °C
View Scheme
参考文献
Duprat De Paule, Sebastien; Jeulin, Severine; Ratovelomanana-Vidal, Virginie; Genet, Jean-Pierre; Champion, Nicolas; Deschaux, Gilles; Dellis, Philippe
Organic Process Research and Development, 2003 , vol. 7, # 3 p. 399 - 406