8-甲氧基-1,4-萘醌合成路线 （共 40 条）
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Krohn, Karsten
Tetrahedron Letters, 1980 , vol. 21, p. 3557 - 3560
反应条件
1: 10 percent / NaN3 / acetic acid; H2O / 48 h / Ambient temperature 2: 44 percent / H2SO4, H2O / H2O / 0.08 h / Heating View Scheme
参考文献
Inagaki, Ryuta; Ninomiya, Masayuki; Tanaka, Kaori; Watanabe, Kunitomo; Koketsu, Mamoru
Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 6 p. 670 - 673
反应条件
1.1: Na2S2O4 1.2: 85 percent / K2CO3 / diethyl ether 2.1: 60 percent / Br2 / CCl4 3.1: tBuLi / diethyl ether / -78 °C 3.2: 100 percent / diethyl ether / -78 °C 4.1: 80 percent / PCC / CH2Cl2 5.1: 53 percent / NaOAc / PdCl2(PPh3)2 / N,N-dimethyl-acetamide / 0.02 h / 140 °C / microwave irradiation View Scheme
参考文献
Qabaja, Ghassan; Jones, Graham B.
Tetrahedron Letters, 2000 , vol. 41, # 28 p. 5317 - 5320
反应条件
1: toluene / 5 h / 110 °C 2: 60 percent / MnO2 / CHCl3 / 30 h / Ambient temperature 3: 74 percent / 33 percent HBr / acetic acid / Ambient temperature View Scheme
参考文献
Chigr, Mohamed; Fillion, Houda; Rougny, Annie
Tetrahedron Letters, 1987 , vol. 28, # 39 p. 4529 - 4532
反应条件
silver(l) oxide in dichloromethane
25 h; Ambient temperature;
参考文献
Inagaki, Ryuta; Ninomiya, Masayuki; Tanaka, Kaori; Watanabe, Kunitomo; Koketsu, Mamoru
Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 6 p. 670 - 673
反应条件
hydrogenchloride in tetrahydrofuran
T=60°C; 12 h;
参考文献
Crouse, David J.; Wheeler, Margaret M.; Goemann, Marti; Tobin, Paul S.; Basu, Swapan K.; Wheeler, Desmond M. S.
Journal of Organic Chemistry, 1981 , vol. 46, # 9 p. 1814 - 1817
反应条件
argentic oxide; nitric acid in acetone
T=20°C;
参考文献
Tanoue, Yasuhiro; Sakata, Kazunori; Hashimoto, Mamoru; Morishita, Shin-Ich; Hamada, Moritsugu; Kai, Norihisa; Nagai, Takeshi
Tetrahedron, 2002 , vol. 58, # 1 p. 99 - 104
反应条件
bis-[(trifluoroacetoxy)iodo]benzene in water; acetonitrile
T=0°C;
参考文献
Barret; Daudon
Tetrahedron Letters, 1990 , vol. 31, # 34 p. 4871 - 4872
反应条件
sulfuric acid; chromic acid in acetone
0.333333 h;
参考文献
Swenton, John S.; Anderson, D. Keith; Coburn, Charles E.; Haag, Anthony P.
Tetrahedron, 1984 , vol. 40, # 22 p. 4633 - 4642
反应条件
Fremy’s salt in chloroform
10 h; pH 6;
参考文献
Saa, Jose M.; Morey, Jeronimo; Rubido, Carmen
Journal of Organic Chemistry, 1986 , vol. 51, # 23 p. 4471 - 4473
