3,5-二苯基-2-异恶唑啉合成路线 （共 45 条）
反应条件
10 w/w silver nitrate/silica gel in dichloromethane
T=20°C; 0.25 h; regiospecific reaction;
参考文献
Knight, David W.; Proctor, Anthony J.; Clough, John M.
Synlett, 2010 , # 4 art. no. D31809ST, p. 628 - 632
参考文献
Moriya, Osamu; Urata, Yoshikiyo; Endo, Takeshi
Journal of the Chemical Society, Chemical Communications, 1991 , # 13 p. 884 - 885
反应条件
nitrosyl chloride in dichloromethane
T=-50 - -40°C; 3 h; Product distribution; Further Variations:SolventsTemperatures;
参考文献
Bondarenko; Gavrilova; Saginova; Zyk
Russian Journal of Organic Chemistry, 2003 , vol. 39, # 7 p. 1021 - 1024
反应条件
pyridine
3 h; Heating;
参考文献
Shimizu, Tomio; Hayashi, Yoshiyuki; Furukawa, Nobuhiro; Teramura, Kazuhiro
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 1 p. 318 - 320
反应条件
1: N-chlorosuccinimide, pyridine / CH2Cl2 / 1 h / Heating
2: Et3N / CH2Cl2 / 1 h / Heating
View Scheme
参考文献
Nagarajan, A.; Pillay, M. Krishna
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 4 p. 471 - 474
反应条件
1: 82 percent / N-chlorosuccinimide, Et3N / CH2Cl2 / 24 h / 0 °C
2: various solvent(s) / 4.5 h / Heating
View Scheme
参考文献
Ooi, Ngan Sim; Wilson, David A.
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4726 - 4736
参考文献
Chen; Lam, Yulin; Lai, Yee-Hing
Organic Letters, 2003 , vol. 5, # 7 p. 1067 - 1069
反应条件
1.1: sodium hydroxide / ethanol; water / 0.17 h / 0 - 5 °C
1.2: Reflux
2.1: hydroxylamine hydrochloride; [N-butylthiazolium][Br] / 0.87 h / 20 °C / Ionic liquid
View Scheme
参考文献
Safaei-Ghomi, Javad; Ghasemzadeh, Mohammad Ali
Journal of the Serbian Chemical Society, 2012 , vol. 77, # 6 p. 733 - 739
反应条件
ethanol; hydroxylamine hydrochloride; sodium carbonate
参考文献
Rupe; Schneider
Chemische Berichte, 1895 , vol. 28, p. 965
反应条件
in various solvent(s)
4.5 h; Heating;
参考文献
Ooi, Ngan Sim; Wilson, David A.
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4726 - 4736
